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GS-6201 Size:Contact [email protected] for quotation inhibits cellular EGFR and ErbB2

SKU: 55020437701

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Description

inhibits cellular EGFR and ErbB2 autophosphorylation with IC50s of 7

PubMed PMID: 29108673

which disrupts MYC/MAX interaction

InChi: InChI=1S/C17H18N6O8S/c18-14-11-15(20-6-19-14)23(7-21-11)17-13(26)12(25)10(31-17)5-30-32(28

Solubility: DMSO : ≥ 100 mg/mL (276

GS-6201 Size:Contact [email protected] for quotation inhibits cellular EGFR and ErbB2GS 6201 (CVT 6883) is a selective adenosine A2B receptor antagonist. GS 6201 displays high affinity and selectivity for the human adenosine A2B receptors (Ki=22 nM). GS 6201 reduces caspase 1 activity in the heart, and attenuates cardiac remodeling after acute myocardial infarction (AMI) in the mouse. GS 62013 attenuates the airway reactivity induced by NECA, AMP, or allergen in sensitized mice. Product information CAS Number: 752222 83 6 Molecular

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